The success of infertility treatment using Assisted Reproduction Technologies (ART) program largely depends the quality of cultured embryos and sustainable high pregnancy rate balanced by a low incidence of multiple gestations. Modern molecular genetic approaches make it possible to obtain a genetic profile which gives the opportunity to select for transfer embryos without chromosomal abnormalities. Preimplantation Genetic Diagnosis (PGD) was developed as a method to improve ART outcomes by selecting chromosomally normal embryos from those which potentially have lethal forms of genetic disorder. PGD can also improve ART success by increasing the implantation rate and reducing pregnancy losses.
There have been many new developments in the field of PGD especially in genetic analysis that enable the screening of all chromosomes from a single cell and more efficient methods of detection of single gene defects. There is a need to inform geneticists, embryologists, specialist in the area on these new technologies, their use and application in treatment and counseling of affected individuals.
This course is designed to use lectures, hands on practical and demonstrations of cleavage stage and blastocyst biopsy of mouse embryos to equip participants with a comprehensive knowledge and understanding of embryo biopsy and its application in PGD. Participants will not become competent at these techniques but will have enough hands on to go away and practice in their own laboratory setting. The course will also allow scientists to discuss the technology with their peers and with experts in the field.
Course Duration: 3 days.