Certificate Course in Preimplantation Genetic Diagnosis (PGD)

Course Description

The success of infertility treatment using Assisted Reproduction Technologies (ART) program largely depends on the quality of cultured embryos and sustainable high pregnancy rate balanced by a low incidence of multiple gestations. Modern molecular genetic approaches make it possible to obtain a genetic profile which gives the opportunity to select for transfer embryos without chromosomal abnormalities. Preimplantation Genetic Diagnosis (PGD) was developed as a method to improve ART outcomes by selecting chromosomally normal embryos from those which potentially have lethal forms of genetic disorder. PGD can also improve ART success by increasing the implantation rate and reducing pregnancy losses.

This course will fo­cu­s on ge­ne­tic as­pects that have im­pli­ca­tions on human fer­ti­lity and the re­pro­duc­ti­ve op­tions in couples who carry ge­ne­tic di­sea­ses and with a risk of ch­ro­mo­so­me ab­nor­ma­li­ties. In the end, it in­tro­du­ces the participants to ge­no­mics and sys­tems me­di­ci­ne in the field of as­sis­ted re­pro­duc­tion.

Course Objectives

This course is designed to use online lectures, hands on practical and demonstrations of cleavage stage and blastocyst biopsy of mouse embryos to equip participants with a comprehensive knowledge and understanding of embryo biopsy and its application in PGD. Participants will not become competent at these techniques but will have enough hands on to go away and practice in their own laboratory setting. The course will also allow scientists to discuss the technology with their peers and with experts in the field.

Intended Learning Outcomes

Upon successful completion of this course, it is expected that each participant will be able to:

  1. Demonstrate increased knowledge and understanding of PGD
  2. Discuss the methods of analysis to detect single gene defects, aneuploidy and mitochondrial disorders.
  3. Discuss the Outcome and implications of PGD.
  4. Discuss the ethical implications and dilemmas in PGD

Target Audience

The course is suitable for anyone wanting to learn more about PGD, including nurses, scientists, clinical embryologists, geneticists, an­dro­lo­gists, re­sear­chers, Gy­ne­co­lo­gists, Phy­si­cians, Re­si­dent Gy­ne­co­lo­gists and Gra­dua­tes and Stu­dents in Bio­me­di­cal Scien­ces (Bio­logy, Me­di­ci­ne, Ve­te­ri­nary, Bio­che­mis­try, Phar­macy, etc.).

Course Duration

This 3-day, clinically oriented, interactive, hands-on training course offers advanced lectures complemented hands-on activities and discussion with experts.